Monday, September 30, 2019

Crisis hostage management/criminal justice Essay

It is saddening when every day we read about reports of hostage taking happening all over the world. Reports from police intelligence departments across the world indicate that, hostage taking cases ranges from kidnapping of infants to taking hostage of crew of big water vessels, as is rampant along the coast of Somalia in Africa. US is not an exeption, infact many cases of hostage taking have been reported especially in the southern region states. An example of hostage taking case happened at Hillary Rodham Clintons campaign offices in Rochester, New Hampshire. A nicely dressed grey haired man known as Leeland Eisenberg walked into the offices on a Friday demanding to talk to Hillary Clinton about helping him get mental health care and ended up taking at least five people hostage including an infant. The ordeal went on until night when the last hostage walked to freedom and the hostage taker peacefully surrendered to the police. Although Eisenberg had a packet of road flares taped on his body, when he was persuaded by the states police negotiator he gave up and surrendered to SWAT police team. According to Hillary Clinton as she addressed a press conference later in Portsmouth that night, Eisenberg was in need of help and was seeking attention in absolutely the wrong way. Eisenberg was held on state charges of kidnapping and reckless conduct, federal charges were being considered. (http://www. msnbc. msn. com/id/22043358). Another hostage taking incidence occurred in Louisville whereby a mother (Gail Lynn Coontz) killed her two children aged 14 and 10 years in their beds and later went to a college she attended with a gun before handing over the weapon to the college’s health counselor. The threat at Louisville University College ended with no injuries about half an hour after it began, but school officials asked police to check on the children, which were found dead with gunshot wounds. Mrs. Coontz was taken to a psychiatric clinic and later taken to Louisville jail. According to university police, Maj. Kenny Brown, she was charged with terrorist threatening for pointing a gun at a police officer. (http://www. msnbc. msn. com/id/23827059). The two counts of hostage taking were very different from one another because the first case was carried out in a mild manner i. e. no violence was reported, the road flares posed some considerable danger, had the suspect decided to use them. The hostage taker was just trying to seek attention according to Hilary Clinton because he unconditionally released the hostages after persuasion by a police negotiator. The second case was a serious one, with the suspect having shot dead her two children earlier on. It’s true that both hostage taking incidences were perpetuated by people who were undergoing psychological problems. For instance Eisenberg had a court case filled by his wife for drug abuse, assault, and verbal threats, while Mrs. Coontz was a window and therefore was stressed by family burden. In both incidences of hostage taking, the hostage takers were persuaded into giving up peacefully, i. e. they never put up any violent resistence. in view of the US governments policy on hostage taking threats, based on past experience, making concessions that benefit hostage takers in exchange of release of hostages increased the danger that others will be taken hostage. At the same time the US government always makes every effort to contact the captors or even their representatives so as to secure the release of hostages. under current US law, 18 USC 1203(act for prevention and punishment of the crime of hostage taking, enacted oct 1984),seizure of a US citizen as a hostage anywhere in the world is a crime and therefore subject to investigation by the Federal Bureau of Investigation and to prosecution by US authorities (http://www. state. gov/r/pa/prs/ps/2002/8190. htm. ) In the first incidence Eisenberg was sweet talked to by a state police negotiator into giving up and surrendering peacefully to the police. And in the second case Mrs. Coontz although pointed a gun to police a officer she voluntarily gave out the gun to the college health counselor. This shows clearly that the negotiators played their part professionally and with a lot of patient. From both counts it’s evident that very minimal force was applied by the police to free the hostages. In the first incidence for instance, although police camped outside the building they never attempted to use excess force lest they provoke the hostage taker into doing a nasty action. Similarly, in the second incidence police played safe until Mrs. Coontz surrendered the gun to the college health counselor voluntarily. Therefore the outcomes of both cases of hostage taking were a success on the part of police since no one taken hostage was injured and the suspects were apprehended. The articles from which I extracted these two hostage taking counts were fairly written, providing detailed information about the hostage takers, and the hostage taking incidence. But the part on negotiation between the suspects and the negotiators was not well expounded in both counts. Readers would want to know the agreements leading to the softening of hostage takers and hence giving up. The writers also gave very little coverage on police action about the incidences. The motive of the killings of the two children by their mother should have been provided . References: A man takes more than five people hostage at Sen. Hilary Clinton’s campaign office in Rochester N, H, available at; 1) http://www. msnbc. msn. com/id/22043358 accessed on April 15, 2008 a mom takes terrorizes a college with a gun after killing her own two children, available at; 2)http://www. msnbc. msn. com/id/23827059accessed on April 15, 2008 US policy on hostage taking threats, available at; 3) http://www. state. gov/r/pa/prs/ps/2002/8190. htm accessed on April 15, 2008

Sunday, September 29, 2019

Martin Luther King Essay

America was experiencing a situation of chaos in the 1950s when the African Americans and the people of color began to rise for the fight of equality and freedom, and racial differences were realized. Initially, blacks and colored were widely discriminated. There were separate restaurants for white and the colored; separate educational institutes and likewise, separate hotels and motels and other public places. Blacks were not given employments on the basis of race and color and the ratio of black working men was almost negligible. They were not even given the right to vote. Cases of police violation on blacks were tremendous. As a result, gradual frustration began bottling up in the blacks. Finally, much to their relief, a decision by the Supreme Court, Brown v. Board of Education was issued in favor of the blacks. This decision given on May 17, 1954, recognized the discrimination against blacks in the field of education and declared that separate educational institutes resulted in unequal educational opportunities. Thus, it ordered all states to combine the blacks and white into same classrooms. However, the country, particularly the Southern part of America, was reluctant in carrying out the court order and hence, many years passed but the order failed to be put into operation. That is when Martin Luther King Jr. appeared. King had been working for equality and justice of blacks for a long time and was one of the prominent leaders in this movement. In order to spring the court order into action and protest for freedom, King along with other more than 250,000 individuals led a march to Lincoln Memorial on August 28, 1963, also known as the March on Washington. This rally included many other eminent characters such as actor Sidney Poitier, and labor leader Walter Reuther. All these influential heads addressed the audience and expressed their feelings individually; however, it was King’s speech; ‘I have a dream’ marked a landmark in civil right movement history. (Wikipedia, 1) About Martin Luther King Jr Born in January 15, 1929, in Atlanta, Martin Luther King was the son of Reverend Martin Luther King, Sr. and a brother of two siblings. He earned his Bachelors degree in 1948 in sociology and then completed his Bachelor of Divinity degree afterwards. In 1955, he did his PhD from Boston University. Afterwards, he became a Baptist minister but then turned his focus towards the civil rights movement and fighting for the freedom of the blacks. He contributed to the establishment of the Southern Christian Leadership Conference and also led the Montgomery Bus Boycott. He was the orator of the memorial speech ‘I have a dream’. He received Nobel Peace Price for his efforts to eliminate racial discriminations. He was also declared â€Å"Man of the Year† by Times Magazine. King was shot dead on April 4, 1968 in Lorraine Motel in Memphis. Martin Luther King Jr. Day was later established in his memory. (Wikipedia,1) Analysis of the Speech Style There is an element of emotional appeal in King’s speech. Rich in vocabulary, it is drenched in symbolism. The speech begins with an attention-grasping phrase and positive connotations. In fact, in the entire speech, whenever the future of blacks is mentioned, King has used strong and healthy words reflecting hope and an optimist approach. The first half of the speech; however, exposes the horrible reality the blacks faced. It narrates the story of thousands of blacks who were divested of their basic rights because of their coloring. King has made use of several phrases to describe the gloomy life of African Americans such as â€Å"the life of the Negro is still sadly crippled by the manacles of segregation and the chains of discrimination. † (Alvarez, 339) King’s background as Baptist also came useful in his speech as it reminds many of the blacks’ Baptist sermons. It contains references from Bible; for example, his sentence, â€Å"It came as a joyous daybreak to end the long night of their captivity’ in the second stanza indicates to Psalm 30:5. Other allusions are found from Amos 5:24 and Isaiah 40:4. † (Wikipedia, 1) At the same time, the speech also reflects the Abraham Lincoln’s style in his Gettysburg Address when he uses the term, ‘Five score years ago’. (Public broadcasting service,1) Here again, the purpose of alluding to Lincoln in the commencing lines of speech is symbolic that is, he refers back to a leader who had fought the Southern states over the issue of slavery. In this way, King is reminding the whites that the slaves of in the 19th century and the blacks of 20th century shared a similar tragedy and the same repressive power. After emptying out his feelings of sorrow and despair for the African Americans, the speech then moves to the phase mirroring hope and about demanding their rights. Here, King uses the term ‘check’ to refer to their rights. (Heath, 146) His expressions such as ‘bank of justice’ and ‘riches of freedom’ compel any man of heart to melt and feel their pain. (Heath, 148) They are also an evident of his literacy exposure and knowledge which was rare in blacks at that time. Plus, these words depict a feeling of hope thriving in the speech. The way King demands for blacks’ right is purely beautiful and saintly as he says, ‘And so, we’ve come to cash this check’. (Alvarez, 352) Next, the speech emphasizes the significance of democracy and need to work together to achieve that state of democracy. Here, ‘Now is the time’ has been accentuated four times in the entire paragraph to demonstrate the critical requirement of acting promptly, without any further delay. (Alvarez, 355) He then refers this discrimination as a weakness of America that needs to be removed in order to achieve the nation’s mutual objectives. Here, King has used the technique of reaching the subconscious by using such words such as ‘children of God’ which itself defines that all blacks and whites are brothers. (Wikipedia 1) Hence, in this way, he didn’t have to say it directly and the message was also conveyed. While he talks of brotherhood and the need to put aside the differences and work together, he also issues a warning for the conflicting parties of the consequences if such circumstances failed to occur and promises the nation that they will struggle to fight and rebel until they were not granted their rights. This is evident from this sentence, ‘The whirlwinds of revolt will continue to shake the foundations of our nation until the bright day of justice emerges. ’ (Alvarez, 338) Nevertheless, King was against violence and sermonized the message of peace. Hence, the main objective of King in this rally was also to communicate his message in a non-violent manner. After encouraging the blacks to continue the fight, the speech moves to its second half – the part about his dream –an American dream. Here, ‘I have a dream today! ’ is repeated at intervals to indicate that the dream must be accomplished immediately and not in some future time. The most popular phrase of this speech ‘I have a dream’ is repeated eight times. (Wikipedia, 1) In this part of the speech that is about his dream, he has offered the image of a united country; a country free of discrimination and hatred; a liberal state. This part is highly rhetorical and lulls the audience into another world the world he yearns to create. His words carry such weight that the audience is bound to share his dream even if they deny it. At the end of the speech, he has named several different states of America. The reason was to make it clear that they want respect, dignity and equality in not just some parts of America but in fact, the entire country. This point was explicitly a clear indication for the Southern states. The concluding stanzas contain a stimulating phrase, ‘Let freedom ring! ’ and ‘Free at last! ’ (Alvarez, 351) The absorbing aspect of this speech is its rhythmical flow. The speech begins with a background of the black citizens’ existing situation and the crisis they are facing. It then proposes the solution to their dilemma; followed by the explanation of the reason of why this solution should be implemented. For this part, King uses number of tools such as facts and emotional appeal. At the end, in order to provoke the feeling of urgent execution of his solution, he shares with the audience a stirring dream i. e. his vision of the ideal situation that would prevail if his proposed solution was put into practice. Techniques Used The climax of the speech is distressing yet uplifting. The beginning stanzas reveal the sad state of blacks in America but the approach of the speech is highly optimistic and inspires the blacks to continue their struggle and the whites to bury their axes and embrace their black brothers. The technique of anaphora has been widely employed. Anaphora is the repetition of same word or phrase again and again at the beginning of sentences. For example, the most extensively used anaphora, also the title of this speech, is ‘I have a dream’. Similarly, other examples of this tool are ‘One hundred years ago’, ‘Let freedom ring’, and ‘With this faith’, along with many others. (Wikipedia, 1) The speech is filled with metaphors. For instance, ‘long night of their captivity’ refers to their sufferings and ‘nation’s capital to cash a check’ points to their purpose of protest. At the same time, ‘this nation will rise up’ is again an indication of the coming revolution. Similarly, ‘I have a dream that my four children’ refers to the black community in reality and the word my gives it a personal touch. (Heath, 160) In fact, King has personalized the entire message by using the words you, my and me. The wealth of this speech is its exquisite vocabulary. Words are skillfully manipulated in such a way that they attach a new meaning to every phrase. The popularity of this speech also owns to this factor. In addition, the quantity and quality of information and words reveal King’s extensive research done before delivering the speech, plus his vast knowledge since it contains references from the Bible, The Gettysburg Address and the US Declaration of Independence. (Public broadcasting service,1) Hence, King has used various techniques and tools in this address including facts, anaphora, metaphors, motivation, visualization, arguments and persuasion. The entire speech is highly figurative and symbolic. In fact, the rally outside the Lincoln’s Memorial is symbolic in itself: they were standing outside the steps of Lincoln Memorial i. e. the memorial of a leader who abolished slavery in the Southern states. (Wikipedia, 1) Conclusion The most distinguished fact about this march was its non-violent approach and this speech is its leading example. While its majority of audience was black; its main target was the white people. While he talked of revolution; his speech contained a message of peace. It was able to answer the meaningless questions of the opposing parties and warn them of the consequences of denying the blacks their rights without any form of hostility. In other words, it instilled in the whites a feeling of guilt and humbleness which proved to be enough to achieve their objective. At the same time, it prodded the colored citizens to keep their hopes high and not to rest until they were ‘free at last! It also motivated President Kennedy to extend his support for this issue. The context of the speech and of the surroundings also became one of the reasons for the popularity of the speech. His speech articulated the feelings of all colored citizens and his voice became the voice of all black citizens. To sum up, King’s speech ‘I have a dream’ touches the depth of the hearts and captures the minds. Its words were able to bring tears in the eyes at that time and carry a captivating effect on the readers even today. With tools such as anaphora and metaphors employed, the speech holds an air of charisma. It shakes the souls of the slumbering and the unjust alike. All in all, the linguistic power of the speech is what makes it stand out from the rest and gain the status of one of the most influential speeches ever delivered. Bibliography Alvarez, Alexandra. â€Å"Martin Luther King’s ‘I Have a Dream’: The Speech Event as Metaphor,† Journal of Black Studies 18 1988: 337-57. Heath, Robert. â€Å"Black Rhetoric: An Example of the Poverty of Values† Southern Speech Communication Journal 39 1973: 145-60

Saturday, September 28, 2019

Comprehensive Annual Financial Report Briefing

Comprehensive Annual Financial Report Briefing Abstract The City of Detroit, founded in 1701, and incorporated in 1806, is in Wayne County, State of Michigan. Detroit is on an international waterway, which connects by means of the St. Lawrence Seaway to seaports around the world. Existing as the largest city in the State of Michigan, Detroit is notorious for its tradition in automotive and is a colloquialism for the automobile industry in the United States. Detroit is also known for its popular music legacies, which residents celebrate in several familiar nicknames, Motor City, Motown or simply the â€Å"D. In a city, whose population is likely at 951,270, Detroit is also known for its liquor distribution during the prohibition in 1920. Each year, government entities, such as the City of Detroit is required to compile a comprehensive annual financial report, or CAFR, complying with the governmental accounting standards board accounting requirements. Comprehensive annual financial re ports are detailed presentations of an entities financial condition, reporting on annual activities and balances.This official statement also includes a letter of transmittal, manager’s discussion and analysis, and has four sections: Introduction, financial section, statistical section, and compliance section. This briefing will review and discuss the comparison of governmental accounting and profit financial accounting. This briefing will also detail how to understand governmental reporting and reporting entities. Last, this briefing will outline management discussion and analysis reports for the state of Michigan. Comprehensive Annual Financial Report BriefingComparison of Accounting Practices Business reports, to include financial reports often refer to the terms nonprofit or not-for-profit, profit, and for-profit to describe an entity classification. These terms are significant as they determine the types of accounting transaction and activities covering a period. Althoug h accounting practices, and activities are most associated between operations of a business enterprise; those of profit, accounting is not restricted to businesses. It also deals with non-business operations.Government or nonprofit entities accounting, being a separate division of accounting, has various accounting practices of which they operate; however, have the same principles. These practices and principles are different from those of for-profit entities (businesses) such that for-profit entities focus on wealth creation, where governmental entities are budget-driven. Budgets’ are key fiscal documents and is the culmination of the political process. For example, according to â€Å"Comprehensive Annual Financial Report – City Of Detroit† (2010), the City’s 2010 General Fund Budget is $1. 8 billion.The city also reports that this budget is void of additions or material changes to existing taxes (Budget to Actual Comparison– General Fund). In a s imilar manner, businesses rely on annual reports to provide shareholders and other interested parties pertinent information about the entities activities and financial performance. Profit margins prove the financial health of a business, although budgets are internal communications to measure results. The key difference in the reporting for the two classifications is that the budget (nonprofit) is a forward communication, while the annual report (profit) is a historic communication.Government Reporting and Reporting Entity Government reporting entities are made up of organizations of which the government controls. The key point to consider about government reporting agencies is to ascertain which public sector the government controls. Reporting entities are the assets, liabilities, revenues, expenses, and cash flow of a board, department, agency, and fund included in a government financial statement summary. Government entities are often made up of additional nonprofit organization, and for-profit organizations called component units.These units are legal and separate entities where the state is accountable. Exclusion of component units alters the state’s financial statement in such a way that it would present misleading or incomplete (â€Å"Office of Financial Management†, 2012). Just for clarity, according to â€Å"Governmental Accounting Standards Board† (2013), the financial reporting entity consists of (a) the primary government; (b) organizations for which the primary government is financially accountable; and (c) other organizations for which the nature and significance of their elationship with the primary government are such that exclusion would cause the reporting entity's financial statements to be misleading or incomplete (Summary of Statement No. 14 The Financial Reporting Entity (Issued 6/91)). With that in mind, governments are likely to construct separate legal entities to perform governmental duties. For example, the City of Detroit has nine legally separated organizations, which make up their component units.For instance, the Economic Development Corporation, and Museum of African American History are two of the nine component units included in the government reporting Comprehensive Annual Financial Report – City of Detroit. (2010). Considering reporting entities, the Statement of Financial Accounting Standards No. 94 best defines and prescribes the recommended treatment. For example, the Statement of Financial Accounting Standards prescribes that consolidated reporting is the only appropriate method to report. Management Discussion & Analysis (MD)This section of the comprehensive annual financial report is required to summarize an organization’s annual results, providing a managerial opinion on the financials, addressing discussion of risks, comparisons to previous years, and a breakdown of financials according to sections and locations. Management discussion and analysis contains for ward-looking discussion paying close attention to uncertainties and the manager’s perception of opportunities and risks. The manager also highlights factors faced that are out of his or her control.For example, the comprehensive annual financial report: City of Detroit includes in its management discussion and analysis the financial position of the city, with the overview of annual activities ending June 30th 2010. The financial highlights include the government’s net asset totals with explanation of increases or decreases Comprehensive Annual Financial Report – City of Detroit. (2010). Reference(s): Comprehensive Annual Financial Report – City of Detroit. (2010). Retrieved from http://www. detroitmi. gov/†¦ /CAFR/2010%20CAFR%20draft%20122010%.. Copley, P. A. , & Engstrom, J. H. 2011). Essentials of accounting for governmental and not-for-profit organizations (10th ed. ). New York, NY: McGraw-Hill. Governmental Accounting Standards Board. (2013). Ret rieved from http://www. gasb. org/ Granof, M. H. , & Wardlow, P. S. (2011). Core concepts of government and not-for-profit accounting (2nd ed. ). New York, NY: Wiley & Sons. Office of Financial Management. (2012). Retrieved from http://www. ofm. wa. gov/policy/glossary. asp Wilson, E. R. , Kattellus, S. C. , & Reck, J. L. (2010). Accounting for governmental & nonprofit entities (15th ed. ). New York, NY: McGraw-Hill.

Friday, September 27, 2019

The Culture War and Multiculturalism in Ishmeal Reeds Japanese by Essay - 1

The Culture War and Multiculturalism in Ishmeal Reeds Japanese by Spring - Essay Example 23. 1993).† Reed consequently touches on the careerist academics as he attacks them for their complicity in relation to the Ivory Towers that served as a sign of white supremacist structure of power. From the novel, it is apparent that there is need for persons from different cultures to become involved in order to enhance in integrating with each other. In his work, Reed presents Culture war as a tool that promotes multiculturalism because it serves as the cause of conflict among individuals from different cultural groups. The satire directed at these debates not only result from Reed’s success in presenting a stinging critique especially through an analysis of the Afro-Asian towards white supremacy as well as American imperialism. In an effective manner, the author portrays how individuals defending white Western view of history focused on trafficking everything in a revisionism manner as well as a â€Å"feel-good ethnocentrism† an approach used to attribute to multiculturalists. Based on the concepts that Ishmael Reed depicts, it is right to classify the novel as a â€Å"critical multiculturalism.† The term ‘critical multiculturalism’ serves as an indication that the piece of literature is out to expose fissures, tensions as well as possible contradictory demands resulting from multiple cultures as opposed to celebrating multiculturalism in an appreciative manner. Reeds goes further to dig deep in presenting the meaning of ‘culture war’ where he present s an absurd comic potential as he insists that the real wars of the 20th century that occurred in the U.S are similar to rhetoric of cultural wars. The opening paragraph of the literary material serves in presenting the creativity of the author through presentation of an effective examination of multiculturalism as well as academia to the later emphasis on

Thursday, September 26, 2019

Historic Event in Middle East Essay Example | Topics and Well Written Essays - 750 words

Historic Event in Middle East - Essay Example In 1917, Britain issued Balfour declaration which was seen as an attempt to support Jewish. The declaration however stated that Britain's support for the creation of Jewish national home in Palestine without violating civil and religious rights of the non-Jewish communities. By the year 1923 Britain had received two mandates a provisional mandate over Palestine and another east of river Jordan Arabs apposed the idea of Jewish national home which lead to a Palestine, Arab nation movement in early 1930s over 100,000 Jewish refugees came to Palestine from nazi Germany and Poland) which made the Arabs organize a general uprising that paralyzed Palestine in the late 1930s. In 1939 British began to limit Jewish immigration and land purchases and it was to be done under Arabs approval only (Mendelsohn, 1989) During World War II, most Palestinian Arabs and Jews stopped their resistance to the British rule and joined the allied forces. After World War II Zionist wanted British to allow immigration of the holocaust survivors they therefore used force to stop Great Britain from limiting Jewish immigration into Palestine. The United Nations special commission on Palestine recommended that Palestine be divided into Arab state and Jewish state also Jerusalem to be put under international control. The UN general assembly adopted this plan on November 29 1947, which could lead to the birth of Israel. Arabs rejected the move and fighting broke immediately. On 14th May 1940, the Jews proclaimed the independent state of Israel and the British withdrew from Palestine the next day neighboring Arabs nations attacked Israel. (Abboushi, 1987) The impacts of these events on today's world are:- It's the oppression of Jews in Eastern Europe that resulted in mass emigration of Jewish refugees who occupied Palestine with an aim of making it an independent Jewish nation the impact today being continued on and off violence between the pales tines and Israelites since then. The pales tines are fighting for the land back a thing that the Zionists can not allow. The fact that British handed over Palestine to the Zionist brought animosity between the Palestinian Arabs and the Jews and this has led to the United Nation spending a lot of money in the peace keeping initiative which is aimed at restoring calm between the two parties. Security uncertainty in the Middle East has also impacted heavily on the oil prices with experienced price fluctuations depending on the political climate in the Middle East. Cold and physical war between Americans ad Arabs came as result of the emigration of Jews from Eastern Europe due to oppression. The Americans are fighting in favor of the Jews with whom they are known to have the same origin. Lastly, the late 1800's oppression of Jews in Eastern Europe had a very strong impact on today's world because the fact that the Jews occupied 'foreign land' has led to suicide bombers. This are Palestinian terrorists who are ready to

Advantages Of A Collaborative Role Among Organizations Essay

Advantages Of A Collaborative Role Among Organizations - Essay Example Collaboration is beneficial among organizations due to the results it yields for both organizations and their clients. Collaboration refers to the relationship between independent organizations that involves coming together to share in either resources or ideas. It often occurs when organizations believe they can accomplish more when together than when they are independent entities. Once organizations come together and work as one, they pose a threat to their competition. This is because; they work as one towards a common goal and do not have to compete against each other. It also increases the rate and speed of innovation for organizations that collaborate, as they share information and ideas openly. Collaboration, also, brings together organizations with different capabilities in regard to the resources they can access. Therefore, upon forming a cooperative relationship, they tend to advance their abilities and skills. From this, their competitiveness improves and so does their sur vival in the market. This is particularly so for organizations with fewer resources, but have immense potential to be successful once they work together with those who have resources. Collaborative roles among and between organizations are beneficial to all firms involved as they come together to lessen the risk incurred to any of them when working alone. Collaboration creates a safety net for all involved, as they can contribute to bailing each other out. Clients enjoy increased reliability from all organizations involved in the collaboration.

Wednesday, September 25, 2019

Israel and Palestine Assignment Example | Topics and Well Written Essays - 500 words

Israel and Palestine - Assignment Example en attack Jerusalem and Jordan parts controlled by the Israeli while Israelites attack Palestinians in Jordan, Jerusalem and Gaza as a means of retaliation and maintenance of security from what they term as terrorism from the Palestinians. Although the international community has shown interest in reconciliatory and mediation roles, I think the problems of Israel and Palestine can only be resolved by mutual consent by the Jews and the Palestinians. Reconciliation attempts had been made since 1948 when independent Palestine State and independent Jewish State were established (Sela, 2002). The move seemed to bring an end to a serious conflict in the region, but the struggle between the two countries is still on until now. There is need for the Palestinians and the Israelis to change their attitudes towards each other, but this is difficult because each side has strong and radical conviction about their religion, territories, power and security. International community may play the role of advising and encouraging both sides to loosen their demands, but the final road to peace will be created by the two nations willingly. The Jews and the Palestinians agreed that Palestine actually deserved to be a free state. West Bank and Gaza was considered to be acceptable locations of the Palestinian State. However, disagreements ensued on the shape and boundaries of those regions (Sela, 2002). The two regions have been the main centers of fights between Israel and Palestine. This clearly shows that the Israeli-Palestine conflicts are fueled by disagreements on boundaries. In this case, no international body will come to the region and tell Israel that this land belongs to Palestine, so just leave it, or tell Palestine the same thing. Israelites and Palestinians alone have the ability to sit and agree on the boundaries, but because each one of them wants to take control, they never seem to come to such an agreement. That is why conflict does not seem to be ending soon. What

Tuesday, September 24, 2019

Why Special Education Students Dont Graduate From High School Dissertation

Why Special Education Students Dont Graduate From High School - Dissertation Example Education Week and the Editorial Projects in Education (EPE) Research Center conducted a national report, which states that approximately 1.3 million youth drop out of high school every year.   However, the White House reports the number as a slightly lower figure of 1.2 million.   A quantitative review of statistics by Sum, et al. shows that â€Å"the incidence of institutionalization problems among young high school dropouts was more than 63 times higher than among young four-year college graduates†.   The need for effective dropout prevention strategies is important because the increasingly significant gap between the student who leaves high school without earning his diploma and the high school graduate has increasingly widened since the 1970s with regard to career mobility, unemployment rates, and wages.    Education Week and the Editorial Projects in Education (EPE) Research Center conducted a national report, which states that approximately 1.3 million youth dro p out of high school every year.   However, the White House reports the number as a slightly lower figure of 1.2 million.   A quantitative review of statistics by Sum, et al. shows that â€Å"the incidence of institutionalization problems among young high school dropouts was more than 63 times higher than among young four-year college graduates†.   The need for effective dropout prevention strategies is important because the increasingly significant gap between the student who leaves high school without earning his diploma and the high school graduate has increasingly widened since the 1970s with regard to career mobility, unemployment rates, and wages.    Research forecasts an even grimmer outlook for special education students who drop out of high school.   These students typically earn less than other dropouts and are less likely to succeed later in life. Feng and Sass report that the likelihood a special education student will drop out of school is double that o f his/her peers. Furthermore, â€Å"compared to their nondisabled peers, students with disabilities are more likely to experience unemployment or underemployment, lower pay, and job dissatisfaction†.This contemporary concern contributes to this qualitative case study which seeks to identify a number of common critical reasons special education students abandon their educational pursuits prior to earning their high school diplomas. Using information from interviews with recent dropouts from Ridgeville High School (pseudonym for a Virginia high school), in conjunction with findings from current literature, this study will contribute to the development of recommendations for more effective dropout prevention programs for special education students. TABLE OF CONTENTS ACKNOWLEDGMENTS iv TABLE OF CONTENTS 2 CHAPTER I 3 INTRODUCTION 3 Background 2 Problem Statement 9 Purpose of the Study 11 Research Questions 12 Hypothesis 12 Identification of Variables 13 Definition of Terms 14 Res earch Plan 16 REFERENCES 20 APPENDIX A 26 CHAPTER I INTRODUCTION High School Dropout Concerns Education Week and the Editorial Projects in Education (EPE) Research Center (2010) conducted a national report, which states that approximately 1.3 million youth drop out of high school every year. However, the White House (as cited in America’s Promise Alliance, 2009) reports the number as a slightly lower figure of 1.2 million. A quantitative review of statistics by Sum, et al. (2009) shows that â€Å"the incidence of institutionalization problems among young high school dropouts was more than 63 times higher than among young four-year college graduates† (p. 9). The need for effective dropout prevention strategies is important because the increasingly significant gap between the student who leaves high school without earning his diploma and the high school graduate has increasingly widened since the 1970s with regard to career mobility, unemployment rates and wages. Researc h forecasts an even grimmer outlook for special education (special ed) students who drop out of high school. These students typically earn less than other dropouts and are less likely to succeed later in life. Feng and Sass (2010) report that the likelihood a special education student will drop out of school is double that of his/her peers. Furthermore, â€Å"compared to their nondisabled peers, students with disabilities are more likely to experience unemployment or underemployment, lower pay, and job dissatisfaction† (Dunn, 1996 as cited in Levinson and Palmer, 2005, p. 11). This contemporary concern contributes to this qualitative case study which seeks to identify a number of common critical reasons special education students abandon their educational pursuits prior to earning their high school diplomas. Background Because an American’s financial stability and professional achievement have primarily depended on his educational attainment, obtaining a high school di ploma significantly enhances an American’s potential to build a solid foundation for achieving professional success (Shore, 2003). â€Å"

Monday, September 23, 2019

Bibliography of Raphael Linkin Annotated Example | Topics and Well Written Essays - 750 words

Of Raphael Linkin - Annotated Bibliography Example Raphael Lemkin was born in Imperial Russia in the village named Bezwodne. He was referred to as Rafal Lemkin. Lemkin’s parents were Joseph and Bella Lemkin. He had two siblings. His father was a farmer whereas his mother was a highly educated woman who engaged in philosophical, linguistic, and art-related works. Lemkin’s was greatly influenced by his mother and the achievements she was able to attain. At the age of 14years, for example, he was well versed with about 14 languages, an aspect that was difficult to many people (Hovannisian 125). Raphael Lemkin attended a local trade school and upon graduation, he went to Ukraine to study Linguistics at John Casmir University. While at the university, Raphael Lemkin developed an interest in the field of criminology and thus the issue of genocide. This urge made him to enroll in the University of Heidelberg located in Germany for a degree in philosophy. It was later that he studied law and became a prosecutor. He advanced gradually into his lawyer occupation (Hovannisian 127). In regard to his career and work experience, Lemkin worked for different law firms in different capacities. In 1929-1934, Lemkin worked as a public prosecutor in Warsaw as well as a secretary to the Committee on Codification of the Laws of the Republic of Polish. In 1930, he was promoted to be a deputy prosecutor. One of his achievements at this level was the translation of The Polish Penal Code of 1932, from Polish to English. He did this in collaboration with Malcolm McDermott, a law professor at Duke University (Martin par 7). His interest in crime grew day after day and it brought about the issue of genocide which was founded on the American Genocide. The Simile Massacre of 1933 in Iraq also fueled the genocide concept. It was in 1934 that Lemkin resigned his job for a position of a private solicitor.

Sunday, September 22, 2019

To what extent does the media assist or limit the conduct of military operations Essay Example for Free

To what extent does the media assist or limit the conduct of military operations Essay Some form of controversy has been regularly generated between the press and the military especially the question of media access to the battlefield. Conflict between reporter and the military is not new. As war correspondents became of age in the Civil War, the military began its determination to protect its operations. The media have often called this determination â€Å"censorship. † The military/media relationship is seriously degraded because of mistrust between the two entities. Sources of this mistrust are analyzed, to include: cultural differences; the perception of biased reporting; misunderstanding and ignorance; and speculation. In any operation there are many aspects of military/media relations which include operational security, the press pool system, logistics, public opinion, etc. However, there has been animosity between journalists and the military. The military frequently views press as offering only potential harm not benefit (Carruthers, 2000). The press, on the other hand, has a history of being critical of the military. For instance, U.  S. media and professional associations insist that the military must accommodate the press in wartime situations, for three good reasons which include: the press has always been present when troops have been involved; the public has a fundamental right to know; and restrictions put violate the First Amendment. Yet on some ground between the military operational requirement for information to be made available only on a basis of needing to know, and the right of the citizens of a democracy to know about what their military is doing, lies a middle ground (Dandeker, 1995). Generally, soldiers understand fighting and journalists understand communicating, yet none of them knows that the political impact of combat depends on how the fighting is communicated. Hence both sides need one another. Key civilian and military leaders have now embraced the fact that successful inclusion of the press to ensure adequate coverage is not an optional luxury, but rather is a necessity in todays information age and the expectations of the citizens. The benefits gained from the news media coverage of military operations outweigh the drawbacks, and therefore press coverage should be permitted. There is no set solution appropriate for every situation, since every war is unique. But improvements in military planning, officer training, and press indoctrination will help solve some of the current problems in the military/media relationship. How media assist the conduct of military operations In todays technology-driven world, the media is a fourth dimension added to air, land, and sea and the operational commander must contend with this potent entity to be relevant. Moreover, the media is an accelerator of immense importance in todays world in respect to the operational factors of time, space, and force affecting the operational commander decision-making. The reason why the military should engage the media is probably best stated by General (Ret) Dennis J.  Reimer in a 1997 memorandum to his senior Army leaders. â€Å"Our success, as an institution, depends on the degree to which all senior leaders communicate clearly to the people. It is in fact part of your METL [Mission Essential Task List],† said Reimer. To begin with, the military has the need for improved defense related public relations. The media is an important force multiplier, and it must be harnessed to win the battle of the hearts and minds of the people and keep them fully abreast of developments at home and abroad. This will ensure that they are not misled by rumors, propaganda and dis-information; this could happen if they do not have access to a truthful and speedy account of the facts and the progress of events. Secondly, the media is important in projecting the operations to the remotest parts of the country and arousing nationalism and patriotic fervour in the nation. Thirdly, having a media team at each level of command down to the battalion level is of great help to project the activities of the armed forces through films and other means. The procedure evolved provide for regular operational briefings by the operational/intelligence staff at headquarters or by the concerned corps/divisional commanders. Fourthly, training selected service officers and men in media work by running suitable courses for them on a regular basis and also media personnel need to understand the organisation, role, ethos and fighting capabilities of the armed forces and the characteristics of its various units is most beneficial (that is , media-military interface). Fifthly, limiting journalists access to a war can also work against the military. Galloway pointed to the Persian Gulf War as an example. When the war was over you had no proof of the efficacy of your efforts and your soldiers efforts to take up on [Capitol] Hill at a very difficult time when troop cuts, budget cuts, drawbacks are all under way, he said. Despite the constant tension and sometimes opposing goals of the military and the media, the militarys primary role is to support and defend the Constitution of the nation, the First Amendment of which is freedom of speech and of the press. Finally, having media-military interface there is hope for prompt and timely information in an age when news is increasingly being transmitted and used instantly, with TV news being broadcast on the hour, every hour (Krishna, 2000). How media limit the conduct of military operations The longstanding conflict between the news medias need for access and the militarys need for secrecy has continued during the war on terrorism, journalists agree. If anything, the tension between th e two groups has gotten worse. For instance, during the war in Afghanistan, Pentagon senior spokesman Bryan Whitman said the military understands reporters concerns but that the top priority must be troop safety. Ensuring †¦ that what we do with the news media in the Pentagon or in the field doesnt do anything to jeopardize the success of the operation or endanger the personnel that are participating in the military operation †¦ has to be balanced all the time with †¦ how much reporting can be taking place at any given moment, he said. (Wilcox Jr, 2002) But author and former war correspondent Joe Galloway, whose book We Were Soldiers Once †¦ and Young documents the first major U. S. ground battle of the Vietnam War, said that Vietnam changed the mindset of the military because of the open and unrestricted reporting done by journalists. Most of the times, the military is willing to learn, the journalists are not; pointed out by Galloway as evidenced by the numerous invitations he has received from the military to speak about the subject. He has not received any invitations to speak to news organizations or journalism schools. The media is also believed by them reporting from the battlefield turn the people against the military and against the war. Galloway also adds that, while Vietnam remains a model for him in terms of military/media relations, U. S. led military operations in Grenada and Panama were disastrous in terms of the medias ability to cover those conflicts because of military restrictions. Also, keeping the media at a greater distance from combat operations than security requires would contribute to a bitterly adversarial military-media relationship. This, in turn, would likely hurt the war effort in the long run by inviting relentlessly negative coverage and fanning public distrust. Furthermore, the media are a fact of military operations and here to stay as well as being vital to all democratic governments seeking to discharge their duty to explain. Military control of information during war time is also a major contributing factor to propaganda, especially when the media go along with it without question. The military recognizes the values of media and information control very well. The military often manipulates the mainstream media, by restricting or managing what information is presented and hence what the public are told. For them it is paramount to control the media. This can involve all manner of activities, from organizing media sessions and daily press briefings, or through providing managed access to war zones, to even planting stories. Over time then, the way that the media covers conflicts degrades in quality, critique and objectiveness. As one military puts it,† Information is the currency of victory. † From a military’s perspective, information warfare is another front on which a battle must be fought. However, as well as needing to deceive adversaries, in order to maintain public support, information to their own public must no doubt be managed as well. That makes sense from a military perspective. Sometimes the public can be willing to sacrifice detailed knowledge. But that can also lead to unaccountability and when information that is presented has been managed, propaganda is often the result. Finally, the military have had to adapt since 1982 is the speed of reporting made possible by modern communications. Today, a reporter with a digital camera, a laptop and a satellite phone, all of which can fit in a day sack, can file stories minutes after events and even live if they have a bit more by way of equipment. Control is much more difficult if reporters dont need military’s help to file a story. Because they can act so quickly, and are expected to do so by their editors or newsrooms, military dont have the time to ponder at length our response to events, we must respond quickly whilst still, crucially, maintaining accuracy. For instance, this happened on TELIC 1 (Iraq) but, it was not a great success. Conclusion Throughout history, no matter the time or war, there has always been a conflict between the military and the media. The media’s right to a free press conflicts with the military’s concern for operational security. It serves no constructive purpose, however, to ignore this conflict nor does it serve a purpose by adding to it. Therefore, it is time for the military to accept the media as part of the battlefield of the 21st century, and to understand and prepare for the media as it does for other battlefield elements. Commanders should ensure that their troops receive not only the equipment, but also the training to survive in adverse battlefield environments. The point here is to point out that no matter whether the military likes or dislikes the media, the media will be a part of the battlefield environment just as the weather. As is the case with inclement weather, the better the commander plans and prepares his or her troops, as well as themselves for the media, the better they and their troops will do when faced with a reporter. If we are going to get this right, the military must not resort unnecessarily to secrecy or to lightly tarring independent journalists as disloyal. The media should not frivolously cry censorship. And each should work harder to understand the views and accommodate the needs of the other.

Saturday, September 21, 2019

Molecular Mechanisms of Sepsis

Molecular Mechanisms of Sepsis Title: Protein-protein interaction network and functional module analysis to reveal the mechanism of sepsis in polytrauma patients Highlights: We explored the molecular basis of sepsis induced by polytrauma using PPI network. A total of 342 DEGs including 110 up- and 232 down-regulated genes were obtained. TRAF3 was related with the innate immune responses in sepsis. ITGB3 was the key gene involved in coagulation dysregulation in sepsis. CASP6 and RASA1 played key roles in the cell apoptosis mechanism of sepsis. Abstract Objective Sepsis represents the systemic inflammatory response to microbial infection. The pathogenesis of sepsis remains unclear. In this study, we aimed to explore the molecular mechanism of sepsis inpolytrauma patients. Methods The differentially expressed genes (DEGs) between the polytrauma patients with and without sepsis were identified by analyzing the GSE12624 microarray data using the limma package of R. The protein-protein interaction (PPI) network was extracted from the human PPI datasets by using MATLAB. The functional modules in the PPI network were identified by the MCODE network clustering algorithm. The KEGG pathway analysis was performed in each module. The phylogenetic tree was constructed using phylogeny inference package (PHYLIP). Result Total of 342 DEGs including 110 up- and 232 down-regulated genes were obtained. The PPI network identified several hub genes which had more interactions with others, such as TRAF3, ITGB3, CASP6 and RASA1. Further phylogenetic analysis indicated the high conservation of these hub genes. In the module analysis, four significant modules were identified. All the genes (COL1A2, FN1, ITGA2B, ITGB3 and CD36) in module 2 were enriched in extracellular matrix (ECM)-receptor interaction pathway. In module 4, CASP6 and CASP3 were enriched in apoptosis pathway. Conclusion We predicted genes such as TRAF3, ITGB3, CASP6 and RASA1 which were closely associated with sepsis induced by polytrauma. Among them, ITGB3 may play key role in the coagulation dysregulation of polytrauma patients with sepsis, and CASP6 and RASA1 may be the key genes in the cell apoptosis mechanism of sepsis. Keywords Sepsis, DEGs, GO, PPI network, phylogenetic tree Introduction Polytrauma is a syndrome of multiple injuries exceeding a defined severity with sequential systemic reactions that can lead to dysfunction or failure of remote organs and vital systems, which have not themselves been directly injured [1]. Sepsis, as one of the complications of polytrauma [2], is the systemic inflammatory response to microbial infection that often leads to increasing susceptibility to secondary infections, multiorgan failure, and death [3]. A sixteen years clinical study indicated that 10.2% of polytrauma patients infected sepsis during their hospital course [4]. Polytrauma is a major cause of morbidity and mortality in global and sepsis (3.1-17%) is one of the predominant causes of late death in polytrauma patients [5]. The disease severity is increasing according to the order of sepsis, severe sepsis and septic shock in the systemic inflammatory response syndrome (SIRS) [6]. Mortality has been reported to be as high as 45.6% for patients with severe sepsis or septic shock [7]. Based on the pathogenesis of sepsis, many therapies have been applied in the clinical practice such as antimicrobial therapy [8, 9] and hemodynamic support and adjunctive therapy [10, 11]. Currently, the Surviving Sepsis Campaign (SSC) has attempted to increase the awareness and establish the practice guidelines to improve the recognition and treatment for the patients with sepsis [12, 13]. At present, there are four approved mechanisms in the pathogenesis of sepsis [14]. The first one is dysregulated coagulation. Sepsis patients frequently manifest disseminated intravascular coagulation (DIC) with consumption of platelets and prolongation of clotting times [15]. The second one is inflammatory response. The inflammatory response is an important and central component of sepsis because the elements of response drive the physiological alterations that manifest as the SIRS [16]. Third, many cellular aspects become dysfunctional in sepsis which behave either excessive activation or depressed function [17]. The last one is metabolic alterations. It was reported that endogenous glucose production was markedly increased in the patients [18]. However, the specific molecular mechanisms of them remain entirely unclear. In this study, the differentially expressed genes (DEGs) between the polytrauma patients with sepsis and without sepsis were identified. Gene ontology (GO) analysis , protein-protein interaction (PPI) network and phylogenetic tree construction were performed to explore the molecular basis of sepsis induced by polytrauma. Materials and methods Microarray data The gene expression profile of GSE12624 based on the CodeLink UniSet Human I Bioarray platform (GE Healthcare/Amersham Biosciences) was downloaded from National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm.nih.gov/geo/). The dataset available in this analysis contained 70 samples including 34 polytrauma patients with sepsis and 36 polytrauma patients without sepsis. Data preprocessing and DEGs screening For the microarray data, Robust Multichip Average (RMA) in the Affy package of R was used to compute normalized expression measures from the raw expression values. Probe annotation was obtained by using the Bioconductor package. The limma package was used to identify the DEGs with p-value 1 [19]. GO enrichment analysis of DEGs GO analysis was performed using the DAVID online tool (http://david.abcc.ncifcrf.gov/) [20]. For GO enrichment of DEGs, we selected GOTERM_BP_FAT, GOTERM_CC_FAT and GOTERM_MF_FAT as the gene set categories. A p-value of less than 0.05 was set as the cut-off criterion. PPI network construction The human PPI datasets with 108477 interacting protein pairs were downloaded from PINA2 (http://cbg.garvan.unsw.edu.au/pina/interactome.stat.do) at December 26, 2013. The PPI networks of the DEGs in sepsis were extracted from the human PPI datasets by usingMATLAB [21]. The proteins in the network served as nodes and the degree of a node corresponded to the number of interactions with other proteins [22]. The protein with high degree was considered as the hub node. Identification of functional modules in PPI network PPI network visualization and network parameters evaluation were performed by using Cytoscape software. The modules were identified by the MCODE (a cytoscape plug-in) network clustering algorithm with the default parameters [23]. The module with score larger than 2 was considered as significant. KEGG pathway analysis of each module was performed by applying the DAVID annotation tool. Phylogenetic tree construction In this study, we constructed the phylogenetic tree based on the nucleotide sequences to investigate the sequence conservation of the DEGs whosedegree were large than 30. The BLAST program is used to search for homologous sequences of these DEGs. The DNA sequence of these DEGs and their homologous genes in FASTA format were obtained from the nucleic acid database in NCBI (http://www.ncbi.nlm.nih.gov/nuccore). The phylogenetic tree was constructed by using phylogeny inference package (PHYLIP) with the default parameters [24]. The gene conservation was estimated by the distance from gene to the phylogenetic tree root. Result DEGs between the patients with and without sepsis After statistical analysis of the microarray data, a total of 342 DEGs were screened out. Among them, 110 were down-regulated and 232 were up-regulated in sepsis. The top 20 significantly up- and down-regulated DEGs are shown in Table 1. GO enrichment analysis The 342 DEGs were significantly enriched into 95GOterms including 81 biological processes terms, 10 cellular component terms and 4 molecular function terms. The top 10 GO biological processes termswere mainly related to the purine base (purine base biosynthetic process, purine base metabolic process, purine nucleoside monophosphate biosynthetic process and purine ribonucleoside monophosphate biosynthetic process), nucleobase (nucleobase metabolic process and nucleobase biosynthetic process) and regulation of protein modification (regulation of protein modification process and positive regulation of protein modification process). The 10 significantly enriched GO terms of cellular component included four lumen related terms (organelle lumen, membrane-enclosed lumen, intracellular organelle lumen and nuclear lumen), two membrane related terms (extrinsic to membrane and plasma membrane part) and four other cellular component terms (peroxisome, microbody, nuclear body and Golgi apparatus) . For molecular function, four significant GO terms were enriched finally. They were acyl-CoA binding, sons of mothers against decapentaplegic homologue (SMAD) binding, aryl hydrocarbon receptor binding and potassium channel inhibitor activity (Table 2). PPI network of DEGs A PPI network consisting of 225 DEGs and 1048 non-DEGs is shown in Fig. 1. This network included 1145 gene nodes and 1273 interactions. The connectivity degree of each node in this PPI network was calculated and the results of top 20 nodes are listed in Table 3. Among them, the genes CRK (encoding CDC2 related protein kina), RASA1 (encoding RAS p21 protein activator 1), TRAF3 (encoding tumour-necrosis-factor receptor associated factor 3), ZHX1 (encode zinc-fingers and homeoboxes), ITGB3 (encoding integrin ÃŽ ²3), RPA1 (encoding replication protein A1), JAK3 (encoding Janus kinases 3), and CASP6 (encoding caspase-6) with the degree over 30 were selected as the hub genes. Module analysis of PPI network A total of 7 modules were constructed by using MCODE plug-in. After excluding the modules with the score less than 2, 4 significant modules were considered as functional ones associated with sepsis (Table 4). According to the Fig. 2, the numbers of nodes and edges were similar in each model. The detailed results of KEGG pathway analysis for each module are provided in Table 5. For module 1, no pathway was enriched in the KEGG pathway analysis. For module 2, a total of 14 significant enriched pathways were identified. Among them, all the genes in this module were enriched in the pathway of extracellular matrix (ECM)-receptor interaction. In addition, except CD36 (encoding glycoprotein IV), the other four genes (ITGB3 and ITGA2B encoding integrin ÃŽ ±IIbÃŽ ²3, COL1A2 encoding the ÃŽ ± 2 chain of type 1 collagen and FN1 encoding fibrinogen 1) were enriched in the focal adhesion and phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway. There were three significant enriched pathways in module 3. HIF1A (encoding hypoxia inducible factor-1), ARNT (encoding arylhydrocarbon receptor nuclear translocator) and ARNT2 (encoding arylhydrocarbon receptor nuclear translocator 2) were enriched in the pathway of renal cell carcinoma and pathways in cancer. HIF1A and ARNT were enriched in the pathway of Hypoxia-inducible factor 1 (HIF-1) signaling. For the module 4, five significant pathways were found. Among them, CASP3 (encoding caspase 3) and BIRC5 (encoding baculoviral IAP repeat–containing 5 and also called survivin) were enriched in the pathway of colorectal cancer, hepatitis B and pathways in cancer. CASP6 and CASP3 were enriched in apoptosis pathway. CASP3 and RASA1 were enriched in the mitogen-activated protein kinase (MAPK) signaling pathway (Table 5). Phylogenetic tree analysis Based on the result of PPI network analysis, the selected hub genes were chosen to construct the phylogenetic tree. The phylogenetic tree of ZHX1 was unable to be constructed, as only three homologous sequences were searched out. The phylogenetic trees of the other seven hub genes were constructed by the DEGs and their top nine significant homologous genes. The results showed that CRK, RASA1, TRAF3, ITGB3, RPA1 and CASP6 were the genes that were closer to tree roots indicating that the conservation of these genes was high during evolution. However, the conservation of JAK3 was low because of appearing in the late period of evolution (Fig. 3). Discussion Currently, sepsis remains a serious clinical problem. The four approved mechanisms of sepsis were dysregulated coagulation, inflammatory response, and cellular dysfunctional and metabolic alterations. However, the specific molecular mechanisms are still incompletely understood. For better understanding the pathogenesis, we identified and analyzed the DEGs between the patients with and without sepsis. As a result, a total of 342 DEGs including 110 up-regulated genes and 232 down-regulated genes were found. These genes were significantly enriched in GO terms including purine base biosynthetic process, regulation of protein modification process and peroxisome. Among them, the process of purine base biosynthesis is the most significantly enriched process. It was reported that de novo purine biosynthesis was essential for infectivity, growth and virulence of many bacteria in mammals [25]. The pathogenesis of sepsis was related with the bacterial infection [26]. Therefore, the purine base biosynthesis process may associate with sepsis based on the tissue response to bacterial infection. For the regulation of protein modification, Wu et al. reported that the alterations in the phosphorylation of myofibrillar proteins and the Ca2+ sensitivity of myofibrillar ATPase might contribute to alter cardiac function during the progression of sepsis [27]. The cardiac dysfunction was the clinical characteristic in severe sepsis and septic shock [28]. Thus, the phosphorylation of myofibrillar proteins may be related with the sepsis-induced cardiac dysfunction. Furthermore, we mapped the DEGs to the PPI network and identified high conserved hub genes. Among them, the high conservation of CRK, RASA1, TRAF3, ITGB3, RPA1 and CASP6 were proved by the phylogenetic tree analysis. They may be the crucial genes in the pathogenesis of sepsis. For TRAF3, it is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family [29]. This protein participates in the activation of the innate immune response [30]. In the PPI network, TBK1 (encoding TANK-binding kinase 1) was a non-DEG interacted with TRAF3. It was reported that TIR domain-containing adaptor-inducing IFN-ÃŽ ² (TRIF) could interact with noncanonical IKKs (IKKà Ã‚ µ and TBK-1) and IKKÃŽ ¹ (also called IKKà Ã‚ µ) through TRAF3 in the Toll-like receptors (TLR) signaling pathway [31]. The innate immune system constitutes the first line of defense by rapidly detecting invading pathogens through the TLR [32] and is a danger signal in systemic inflammatory response syndrome and sepsi s [33]. Thus, TRAF3 may be the mediator of innate immune responses in sepsis induced by polytrauma. We also performed the modular analysis of the PPI network and four functional modules were identified. Based on the result of the KEGG pathway analysis of each module, we found that the pathways in module 2 and 4 were more related with sepsis. The ECM-receptor interaction pathway was the most significant pathway in module 2 and all the genes of this module were enriched in this pathway. Fibronectin and collagen are the components of ECM [34]. Integrin family are the receptors transducing signals from the ECM [35]. Among them, integrin ÃŽ ±IIbÃŽ ²3 is the platelet integrin promoting theaggregation of platelets [36-38]. Moreover, it was reported that collagen type I could induce the aggregation of platelet [39]. Integrin ÃŽ ±IIbÃŽ ²3 is one of the platelet collagen receptors in platelets [40]. It was reported that platelet-specific elements initiated at the cytoplasmic domains of integrin ÃŽ ±IIbÃŽ ²3, which was a signal that leaded to conformational changes within the extracellular do mains of integrin and expression of the fibrinogen receptor, then the simultaneous occupancy on adjacent platelets of receptors with dimeric fibrinogen molecules leaded to platelet aggregation [41]. In addition, CD36 is spatially associated with the ÃŽ ±IIbÃŽ ²3 integrin on the surface of platelets [42]. Thus, we speculated that the binding of collagen type I and ÃŽ ±IIbÃŽ ²3 might need the participation of CD36, and then conformational changes within the extracellular domains of integrin and the binding between fibrinogen and fibrinogen receptor could lead to platelet aggregation. Disseminated platelet aggregation is one of the characteristics of the DIC in sepsis [43, 44]. The up-regulated expression of ITGB3 in sepsis may lead to the disseminated platelet aggregation. Hence, we concluded that the coagulation dysregulation in the polytrauma patients with sepsis may be associated with the increase of disseminated platelet aggregation caused by the up-regulated expression of ITGB3. Thus, ITGB3 may play key roles in the coagulation dysregulation of the polytrauma patients with sepsis. Hub nodes CASP6 and RASA1 were predicted to be closely interacted with each other in module 4. Besides, CASP3, TOP1, BIRC5 and AURKB (Aurora B kinase) were also included in module 4. Among them, CASP6 and CASP3 were enriched in apoptosis pathway. It was reported that CASP6 may be associated with the cell apoptosis in sepsis [45] and blocking caspases might have some beneficial effects in decreasing cell apoptosis in sepsis [46]. Thus, we further confirmed that the up-regulated expression of CASP6 may promote cell apoptosis in sepsis. Besides, TOP1 is cleaved late during cell apoptosis by CASP6 and CASP3 [47]. The TOP1 cleavage complexes contribute to cell apoptosis [48]. Therefore, the increase of these complexes induced by the up-regulated CASP6 can promote the cell apoptosis in sepsis. Moreover, full-length TOP1 could induce DNA cleavage by single-strand breaks which is the signal of cell apoptosis [49, 50]. Therefore, the exaggerated gene expression of TOP1 in our study might cont ribute to cell apoptosis in sepsis. In addition, it was reported that CASP3 could modulate a given set of proteins to generate, depending on the intensity of the input signals, opposite outcomes (survival vs death) through differential processing of RASA1 [51]. Some articles reported that low CASP3 activity leaded to the cleavage of the RASA1 protein into an amino-terminal fragment [52, 53]. RASA1 bound BIRC5 is a bifunctional protein complex that can suppress cell apoptosis and regulated cell division, so as to generate anti-apoptotic signals [54]. AURKB exists in a complex with BIRC5 [55]. Considering the up-regulated expression of RASA1 and AURKB, we speculated that there may be a switch mechanism of CASP3-RASA1 in cell apoptosis and BIRC5 and AURKB might play roles in the anti-apoptosis mechanism of RASA1. In summary, CASP6 and RASA1 are the key genes in the pathogenesis of sepsis induced by polytrauma. Conclusion In this study, we obtained four key genes related with pathogenesis of sepsisinduced by polytrauma. Among them, TRAF3 was related with the innate immune responses in sepsis,ITGB3 may play key role in the coagulation dysregulation of the polytrauma patients with sepsis and CASP6 and RASA1 were associated with the mechanism of cell apoptosisin sepsis. For further investigating the association of these hub nodes with sepsis and verifying the role of the interactions among the genes in the pathogenesis of sepsis, more studies are required in the future.

Friday, September 20, 2019

The Community Analysis Of Homeless Families

The Community Analysis Of Homeless Families This paper analyzes the social issues surrounding homeless families and describes the extent of the problem within the U. S. community, while comparing the U.S. community to other communities in other parts of the global system. Causes listed in this paper include unemployment, mental illness, drug or alcohol abuse, and lack of affordable housing. Three theoretical models guide the analysis: social systems theory, functionalist theory and conflict theory. The data come from statistics of homeless families in the U.S. and global communities. These results deliver some evidence for current explanations for homeless transitions, and they propose probable avenues for additional research on the dynamics of homelessness. Macro Community Analysis Homelessness is a significant concern within the U. S. and global community. This situation arises when its individuals are poverty stricken and do not have regular access to affordable housing. In the U. S. in the early 1980s, families with young children became one of the fastest growing segments of the homeless population and now consist of 34% of the homeless population, which includes 23% children and 11% adults (Burt et al., 1999). The issues of homelessness have always been a problem around the world, even though it varies greatly, it has been considered to be one of the oldest social dilemmas in the world. Any day, no less than 800,000 individuals are homeless in the U.S., including about 200,000 homeless families. Most homeless families have incomes below 50% of the federal poverty level that makes it nearly impossible for them to find rental property within their means. To make matters worse, as many as 70% of homeless people struggle with serious health problems, mental an d physical disabilities, and/or substance abuse problems (Burt, 2001). Countries have different ways of reporting homelessness, dissimilar measures with which to define homelessness. Some countries have no policy regarding this condition at all and for that reason are unable to report on the statistics. Causes and Effects of Homelessness As mentioned, homeless is also a global issue and not a problem specific to the U.S. It is estimated to be around 3 million homeless individuals in 15 countries of the European Union. Philip Alston, Chairperson of the UN Committee on Economic, Social and Cultural Rights since 1991 states that on any given night, three quarters of a million people in the United States are homeless; in Toronto, Canadas largest city, 6,500 people stayed in emergency shelters on a typical night in late 1997, a two-thirds increase in just one year (Unicef, 1998). Furthermore, abuse and assault appear to be silent characteristics of homelessness. Studies have frequently found, in the histories of both individuals and families who are homeless, high rates of sexual and physical abuse in childhood, frequent foster care and other out of-home placements, and a variation of other family disruptions. Those that are always getting assaulted by their families might choose to run away and seek shelter in the streets than consent to a life of day-to-day abuse from beatings and molestation. The most significant reasons why people become homeless may be due to the inaccessibility of affordable housing for low income people. Studies show that people are likely to become homeless out of unavoidable situations. There are people who do work but they earn too little to pay for rent, electric, gas, and other housing utilities and expenses. If a person becomes unemployed, they will be unable to pay for anything at all. Homeless Families Demographics Although homelessness is a difficult number to measure, one way to analyze the extent of the problem is through demographics. According to The National Center on Family Homelessness (2008), the typical sheltered homeless family is comprised of a mother in her late twenties with two children. Eighty-four percent of families experiencing homelessness are female-headed. This is due to number of factors: Most single-parent families are female-headed (71%). Single-parent families are among the poorest in the nation and as such, are extremely vulnerable to homelessness Several family shelters do not take men into their programs, causing families to separate when they become homeless Families of color are overrepresented in the homeless population. Nationally: Forty-three percent are African-American Fifteen percent are Hispanic Thirty-eight percent are White, non-Hispanic Three percent are Native American Families experiencing homelessness frequently have limited education: Fifty-three percent of homeless mothers do not have a high school diploma Twenty-nine percent of adults in homeless families are working Forty-two percent of children in homeless families are under age six (The National Center on Family Homelessness, 2008). The lack of reasonable housing has led to high rent payments for families that already struggle to pay their living expenses. These issues force many families to become homeless each day. A solution would be to lower the cost of housing, provide more support for those that are in need, and for the government to recognize that homelessness is a large scale problem. Application of Theory Social Systems Theory Social inequality is shown all over the world stemming from situations of race, gender, and age. An individuals social environment includes all situations a person comes into contact with on a day-to-day basis such as the individuals home, job, and income level, and the social rules that govern them. Person-in-environment refers to interaction between an individual and the multiple systems surrounding that individual, and adaptation refers to ones capability to change in order to adjust to new situations. In order to endure, an individual must be able to function effectively within their social environments (Kirst-Ashman Hull, 2002). The important factor behind the social selection model is that homelessness signifies the final point in a process characterized by the slow reduction of an individuals social and economic resources. As an individuals substance use escalates, the persons financial reserves are exhausted as they sustain an increasingly expensive habit. They either fall into rent debts that leads to eviction (Bessant et al., 2002), or family relationships break down leading to homelessness (Coumans Spreen, 2003). Fountain and Howes found that 63% of their sample of homeless people in Britain named drug or alcohol use as a reason for first becoming homeless. The researchers decided that drug use is traditionally seen as one of the major routes into homelessness, and this was borne out by our survey (Fountain Howes, 2002, p. 10). This compares to the above U.S. percentages that have reported drug and alcohol abuse as one of the causes of homelessness. Functionalist Theory Homelessness can be explained by functionalism, a theory developed by Durkheim. Poverty is best understood from a mixed perspective involving conflict, by Karl Marx and functionalist, by Emile Durkheim. Since poverty certainly plays a role in a homelessness community, this theory certainly applies. In my opinion, functionalist theory explains that our country does actually help those in need but occasionally we can be unsuccessful. This theory continues to remind us to live practically and tells us that the social order does essentially work (Meyerhoff 2006). Regrettably, at this time, scientific studies of family homelessness have been unable to instantaneously reflect all of these probable risk factors. Most of the research can be divided into those studies that present family homelessness as the product of separate faces or of community conditions, without examining both factors together (Shlay Rossi, 1992). Conflict Theory Conflict theory, which is significant to the analysis of the homeless condition, is the belief that the means of mental capability and mental achievement plays a role in the determination of what interests will be articulated effectively. Conflict theory studies the macro level of our society, its structures and organizations. While functionalists dispute that society is held together norms, values, and a common morality, conflict theorists consider how society is held together by power and coercion for the advantage of those in power (Ritzer, 2000). Though individuals and groups appreciating great wealth, prestige, and power have the resources needed to impose their values on others with fewer resources, Max Weber, a theorist viewed a range of class divisions in society as normal, inevitable, and acceptable, as do many contemporary conflict theorists (Curran Renzetti, 2001). Webers theory separated the class of individuals into bourgeoisie and proletariat. Bourgeoisie are those capitalist who possess the means of production while the proletariat is deemed as the working class; they are the ones who sell their own labor power. These groupings show how people are classified according to their status in life. It basically defines the societys state of inequality that is stabilized and reproduced through cultural ideology (Meyerhoff 2006). Social Ill within Turley Homelessness Poverty and inequality continues to afflict many residents in Turley, Oklahoma. The best theory that explains the social ill in Turley, Oklahoma, is conflict theory. One of the conflicts impacting Turley residents is the lack of transportation and close health care facilities. Without access to transportation, residents cannot get to work or to doctors or hospitals easily. Webers theory separated the class of individuals into bourgeoisie the haves, and the have-nots were called proletariat. It would be ideal if Marxs idea of constructing a fundamentally equal society where there is no competition for wealth and power (Meyerhoff, 2006). It is known that several of Turley residents have less than other communities. One of the social ills within the Turley community is the many houses that are abandoned, boarded up, falling down or even burned-out by vandalism, which results in minimal to no housing for Turley residents. Also, from low income or unemployment, this may be caused by lack of transportation. This can result in individuals becoming depressed and utilizing drugs or alcohol as a coping mechanism. Prolonged use of drugs or alcohol may result in a mental disorder. People who have complicated life issues related to mental illness and of drug or alcohol use are the most common people who tend to be homeless. There is a common perception that substance abuse and homelessness are linked, but there is considerable contention about the direction of the relationship (Kemp, Neale, Robertson, 2006; Mallett, Rosenthal, Keys, 2005; Neale, 2001; Snow Anderson, 1993). Many people in Turley, Oklahoma are homeless due to lack of affordable housing and lack of access to health care facilities, both of which makes life worse for residents with mental illness or substance abuse problems. Severe mental illnesses may be caused from substance abuse and affect peoples ability to carry out vital stages of everyday life, such as retaining a job, household management or even self-care. Mental illnesses may also prevent people from forming and maintaining stable relationships or cause them to misconstrue assistance from others and react in an angry manner. This often results in pushing away family, friends and caregivers who may be the force keeping that person from becoming homeless. Some studies indicate that substance abuse is a risk factor for homelessness, whereas others suggest that homelessness induces drug use (Neale, 2001, p. 354). Summary In summary, when comparing the U. S. to other global communities, the causes of homelessness were similar, with poverty being the leading cause. To effectively address homelessness, communities need a clear understanding of the problem and realize that it could affect anyone at any given time. Homelessness continues to be an increasing problem and requires social action to overcome the injustice that those people suffer. A change can be made by building or offering affordable housing units to people with low or very minimal income, as well as shielding families from the abuse they may get exposed to and trying to help guide them in the right path. Finally, through helping communities with programs that assist addicted individuals to overcome their addiction as well as people with mental illness by providing affordable health care programs, the homeless have an opportunity to rise above their current situation. As a Child Welfare Supervisor, I selected this particular social justice issue because several of the children that come into OKDHS custody will age out of the system without a permanent home or family, which results in most of them becoming homeless; this was learned in our Child Welfare Trainings. I wanted to learn more about this ongoing problem and feel it is very important that we help homeless people obtain a better life.

Thursday, September 19, 2019

The Hurricane :: essays research papers

Lyrical Analysis Presentation   Ã‚  Ã‚  Ã‚  Ã‚  On July 17, 1966, in Paterson, NJ, Rubin â€Å"Hurricane† Carter was contending for the heavyweight boxing title, when, one night, he was pulled over and suspected of a murder. There was no evidence or witnesses to prove the Hurricane guilty, but the cops needed somebody to blame; so they fixed the trial, and Rubin received the short end of the stick. He was put away for life for a crime he didn’t commit. This is a true story. The song was written by Bob Dylan to bring Rubin’s situation to the public. Rubin Carter was a black man; so many people, including judges and cops, just turned their head. The Hurricane’s verdict was changed after nineteen years in prison. He is now trying to live the life that was taken from him. Dylan’s song, â€Å"The Hurricane† explains how Rubin Carter was proven innocent, but found guilty.   Ã‚  Ã‚  Ã‚  Ã‚  Shots were fired, and a triple murder was committed. Two people were at the scene, Patty Valentine and a man, but there were no witnesses. The man next to the bodies said, â€Å"I was only robbin’ the register, I hope you understand.† Somehow this burglar is not suspected of the murder.   Ã‚  Ã‚  Ã‚  Ã‚  The number one contender for the heavyweight title is not even near the shootings. It says â€Å"Meanwhile, far away in another part of town, Rubin and a couple of friends are drivn’ around.† But he was pulled over anyway â€Å"just like the before and the time before that. In Paterson, that’s just the way things go. If you’re black you might as well not show up on the street ‘less you wanna draw the heat.† People were very racist back then, and therefore a black man was always suspected before a white man.   Ã‚  Ã‚  Ã‚  Ã‚  The police are at the scene gathering information. The burglar and his partner said they saw two middleweights running, and Patty Valentine agreed with them. A cop sees that the bartenders not dead, â€Å"and though this man could hardly see they told him he could identify the guilty man. The cops have to find a person to blame, and even though it doesn’t say it in the song, Rubin has had trouble with the Chief of Police when he was younger.   Ã‚  Ã‚  Ã‚  Ã‚  Rubin is hauled to the hospital, so that the bartender could identify him. â€Å"The wounded man looks up through his one dyin’ eye, says, wha’d you bring him in here for?

Wednesday, September 18, 2019

Deontologial Theory Essay -- essays research papers

ETHICS Deontological Theory Historically ethics was studied from a philosophical aspect and viewed as the science of morals. Ethics had been defined as the principles of moral conduct that govern our behavior. Our ethical behavior is developed from various factors, to include our environment, family and beliefs. The origins of ethics can be traced back to the fifth century, BC ( Banner, 1968, pg.67). Plato, Socrates and Aristotle are among the early teachers of ethics.   Ã‚  Ã‚  Ã‚  Ã‚  These teachers along with many other philosophers developed and taught numerous ethical theories based on their beliefs. Ethical theories that have evolved through the years include, but are not limited to:  §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  The Greek ethics of Plato, Socrates and Aristotle focused on moral virtues.  §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  The Christian ethics of St. Augustine focused on divine revelation.  §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  The consequential ethical theory of Bentham theorized that the consequences of one’s behavior are crucial when making moral decisions.  §Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  The non-consequential ethics of Kant which viewed an individual’s duty and moral obligation as paramount when faced with an ethical challenge. Contemporary philosophers define ethics as a philosophical examination of the principles of right versus wrong, and view morality as the practice of these principles (Souryal, 1998, pg.17). The study of modern ethics and human behavior is a continuum of the examination of many of the same theories studied by earlier philosophers. One such theory is the deontological theory. This ethical theory is based an individual’s actions and not the consequences of the actions. Deontological is derived from the word deontos, the Greek word meaning duty or obligation. There are two sub-categories of the deontological theory. The â€Å"monistic† sub-category bases morality solely on one virtue. Examples of the monistic category of ethical theories are hedonism and Kant’s duty theory. In the theory of hedonism, pleasure is the only good, and in Kant’s theory on ethics, one’s duty or moral obligation is the sole virtue or value of goodness. The â€Å"multiple† sub-category of ethical theories has a minimum of two values of goodness, such as a woman marrying an intelligent and handsome man. The multiple values of goodness ... ...he human relations aspect of our jobs. Finally, as rational and intelligent individuals we must focus on the beneficial aspects of all-ethical theories and attempt to minimize the non-beneficial components of each theory. We must analyze the ethical dilemma and demonstrate the courage and moral virtue to apply the correct ethical theory that would result in the morally correct resolution to any given ethical dilemma. It is imperative that as rational and thinking human beings we consider the ramification of our actions and conclusively make the morally correct decision when faced with an ethical dilemma in law enforcement. References Albert, Ethel, M., Denis, Theodore C. Denise & Peterfreund, Sheldon P. (1988). Great Traditions in Ethics. Belmont, California: Wadsworth, Inc. Banner William A. (1968). Ethics: An Introduction to Moral Philosophy. New York: Charles Scribner’s Sons. Shapiro, David A. (1999). Choosing the Right to Do. San Francisco, California: Berrett- Koehler Publishers. Souryal, Sam S. (1998). Ethics in Criminal Justice: In Search of the Truth. Cincinnati, Ohio: Anderson Publishing Co.

Tuesday, September 17, 2019

The Magna Carta

1. Magna Carta [1215] (52): The Magna Carta was an agreement that insured protection of noble (feudal) liberties from usurpation by the King. The Magna Carta influenced the development of common law (legal precedent), as well as constitutional principles (as seen in the United States Constitution). 2. Chief Powhatan (59): Chief Powhatan was the chief of Algonquian-speaking villages (Powhatan Confederacy) in eastern Virginia, chief of about 10,000 Indians. Powhatan took 80% of the corn his people grew and traded that and hides for weapons. As a result, the English people took over his lands. . Mercantilism (163): Mercantilism was a national program that said that the total amount of the world’s gold and silver stayed the same and only what percent of that each nation had changed then one nation could only become richer by taking another’s gold and silver and taking over its trade. As a result, nations had to develop and protect its own shipping and had to take advantage of the colonies. 4. London (Virginia) Company (57): The Virginia Company was a joint-stock between the First Colony of London and the Second Colony of Plymouth. King James had them go on a religious mission to bring the Christian religion to the natives of the colonies. The settlers trying to change the natives religion led the relations between the two to become tenser. 5. John Smith (59): John Smith was appointed by the Virginia Company to manage Jamestown. Smith was strict and made everyone work. If settlers bickered, he imprisoned them, whipped them and forced them to work. He bargained with Indians and explored and mapped the Chesapeake region. Because of him, Jamestown survived, but he was not well liked by the colonists. . Jamestown (58): Jamestown was the first permanent colony in Virginia by the Virginia Company. The 105 men built a fort, huts, a storehouse and a church. Trade with the Indians and the teachings of the Indians were the only reason Jamestown initially survived. 7. John Rolfe (62): John Rolfe was the reason tobacco became a popular crop. He got a hold of some seeds and tobacco became popular. It had a big profit and he lped the economy. It also led indentured servants to come over, boosting the population. John Rolfe also married Pocahontas, Chief Powhatan’s daughter. She married John Rolfe and they moved to London. John Rolfe was the reason for the tobacco industry in the colonies and more stability between the colonists and Indians. 8. House of Burgesses: 9. Pocahontas (63): Pocahontas was the daughter of Chief Powhatan. She saved John Smith when he trespassed. Powhatan let Smith go in exchange for weapons, beads and trinkets. She was captured in 1614 by Jamestown to try and blackmail Powhatan. She ended up converting to Christianity, changed her named to Rebecca, and married, had a kid and moved to London with John Rolfe. She was a reason Indians and colonists relations improved. 10. Sir William Berkeley (64): Sir William Berkeley was Virginia’s royal governor starting in 1642 and stayed it for the next 35 years. Berkeley favored the richest planters and the commoners rebelled against him in Bacon’s Rebellion. In the end, Berkeley regained control. 11. Headright System (63): The headright system said that anyone who bought a share in The Virginia Company could get 50 acres and 50 more if they brought servants along. Sir Edwin Sandys instituted this reform. It helped the population grow. 12. Indentured servants (62): Indentured servants were people who couldn’t afford to go to America so in exchange for labor, planters would pay for their ride over. This increased the flow of immigrants to the colonies. 13. Bacon’s Rebellion (65): Lowered tobacco prices, rising taxes and freed servants wanting Indian lands contributed to Bacon’s Rebellion. Bacon’s Rebellion grew out of the hatred for Berkeley for favoring the rich planters and hating commoners. Freed indentured servants wanted land and led them to take the Indian’s land. Berkeley didn’t support them so they rebelled. The planters and Indians started to become violent. In 1676, Bacon defied Berkeley by taking command of a group of frontier men. Bacon wanted all Indians dead and Berkeley didn’t. Bacon’s rebellion was the first struggle of common folk versus aristocrats. Berkeley regained control after hanging 23 rebels. A royal commission made a peace treaty with the Indians. The results of the rebellion were new lands opened to colonists and wealthy become more cooperative with commoners. 14. William Bradford (69): William Bradford led 100 men, women and children to the colonies aboard the Mayflower. He and the pilgrims landed at Plymouth and they built on an abandoned Indian village. Bradford led to the Indians and Pilgrims having better relations with each other and Thanksgiving. 15. City on a Hill (72): John Winthrop envisioned the Massachusetts Bay Colony as a city on a hill. Winthrop used hill metaphorically to show that he felt they would above rest of the colonies. 16. John Winthrop (72): John Winthrop was the first governor of Massachusetts Bay Colony and wanted to use the colony as a refuge for Puritans. He took advantage of the charter by the Massachusetts Bay Company by taking its charter with them, transferring government authority so they could have local control. 17. Pilgrims/separatists (69): The Pilgrims were part of the most radical section of Puritans, the Separatists (Nonconformists). They didn’t like the Church of England and decided it couldn’t be fixed so they would create their own godly congregations. Separatist leaders were imprisoned and sometimes hung. King James I wanted to eliminated them. As a result, they left and went to the colonies to escape. 18. Puritans (68): The Puritans were a group of English Protestants. The Puritans in England executed King Charles and made his son the king. The Puritans settled in New England. They were very religions and claimed to be on a divine mission to create a model Christian society. 19. Massachusetts Bay Colony (72): Massachusetts Bay Colony was intended to be a holy commonwealth. Most of the Puritans there were Congregationalists who formed self-governing churches. 20. Plymouth Colony (69): Plymouth Colony held a land grant but had no charter of government form any English authority. The Mayflower Compact governed it. Its population never rose above 7,000. 21. Mayflower Compact (69): The Mayflower Compact was made by 41 Pilgrim leaders who entered into a formal agreement to obey the laws made by the leaders of their choosing. The Mayflower Compact was the primary source of government for Plymouth Colony. 22. Anne Hutchinson (77): Anne Hutchinson argued with Puritan leaders. She lived in Boston and held sermons in her home. Soon they become popular sermons led by her. She claimed that she got revelations from the Holy Spirit that convinced her that only a few Puritan ministers preached the appropriate covenant of grace. She said the rest of them were â€Å"godless hypocrites† and incompetent. 23. Predestination: Predestination is the Calvinist theory that God has predetermined who will go to heaven and who will go to hell. This led people such as Roger Williams to question why church was necessary. 24. Roger Williams (75): Roger Williams was one of the â€Å"purest of Puritans† and was troubled by the failure of the Massachusetts Nonconformists to get rid of the Church of England. He championed liberty and said that the true covenant was between God and the individual. He posed a question that if one’s salvation depends solely upon god’s grace and you can’t affect it, why even bother having churches? Why not just let people exercise their free will in worship? 25. Pequot War (82): The spark of the Pequot War was when settlers in Massachusetts accused a Pequot of murdering a colonist. The settlers got revenge by setting fire to a Pequot village. As the Pequot’s fled, the Puritans shot and killed them. The Pequot’s refuted by attacking the English. The colonists and their allies-the Narragansett- killed hundreds of Pequots. 26. Iroquois League (96): The Iroquois League was made up for 12,000 people governed by 50 chiefs. The chiefs made decisions for all the villages and acted as peacemakers. They seized Canadian hunting grounds and defeated western tribes to hunt beaver in the region to extinction. French and Indian allies gained the advantage over them and reduced their population by a third. The Iroquois made peace with the French in 1701. 27. Quakers (98): The Quakers were the most influential of the radical religious groups. George Fox founded them in 1647. They were an extremely tolerant group of people. They believed everyone should have complete religious freedom. 28. William Penn (98): William Penn was the founder of the Quaker colony of Pennsylvania. When he took control of Pennsylvania, there was already a scattering of religions and races and he made efforts to bring in more settlers of any religion as long as they believed in God. He offered land and the colony grew rapidly. He purchased land titles from the Indians and even learned an Indian language. The Indians and colonists lived side by side in peace. 29. Atlantic Slave Trade: When plantations increased, the need for slaves increased. This led to the creation of the Atlantic Slave Trade The Atlantic Slave Trade was the selling and transporting of African slaves across the Middle Passage. However, 1 in 7 slaves died during the trip. 30. Stono Slave Rebellion (123): Mistreated slaves rebelled against their masters. The slaves who participated in this rebellion were killed and their heads were set up on mile marks to warn other slaves not to rebel. 31. Triangular Trade (135): New Englanders shipped rum to Africa which they traded for slaves, took the slaves to the West Indies and returned home with molasses which they used to make rum. In another version, they shipped provisions to the West Indies, carried sugar and molasses to England and got good manufactured in Europe. 32. Halfway Covenant (139): In 1662, an assembly of Boston ministers accepted this. It said that baptized kids of church members could get halfway membership and secure baptism for their children in turn. They couldn’t vote in church nor take Communion though. 33. Salem Witch Hysteria (139): In 1691, several teenagers met in the kitchen of the village minister. Soon, the girls began to shout, bark, grovel and twitch for no reason. They told people that three women were Satan’s servants and tormenting them. The three women were arrested. At the hearing, the â€Å"afflicted† girls had fits. One of the accused confessed and gave names of other people who she claimed were working for the devil. The governor disbanded the witch court in Salem and ordered the remaining suspects should be released. Nineteen â€Å"witches† were dead and more than 100 were in jail. Some historians say that it was all about land feuds between people. Most of the accused defied the traditional female roles, which could have been another reason. In 1692, some of the afflicted girls shouted â€Å"a witch† and began acting possessed. No one noticed so the girls stopped and left meaning it all could have been for attention. 34. Ben Franklin (150): Ben Franklin published Poor Richard’s Almanac in 1732, which was a collection of homely maxims on success and happiness. He founded a library, a fire company, helped start University of Pennsylvania and organized a debating club that became the American Philosophical Society. He created the Franklin stove, lightening rod, and glass harmonica. He was a freethinker with no true religion. He believed that people could unlock the mysteries of the universe and shape their own destinies. 35. Poor Richard’s Almanac (150): Poor Richard’s Almanac was written in 1732 by Ben Franklin. It contained a collection of homely maxims on success and happiness. 36. Jonathon Edwards (154): Jonathon Edwards was a Congregationalist minister in Massachusetts. He believed that Christians became too preoccupied with money and that religion had become too intellectual causing it to lose its emotional force. He didn’t like people who had cast off religion. He described hell and heaven, which in turn led people to become more spiritual again. 7. George Whitefield (155): George Whitefield was a minister and the catalyst of the Great Awakening. He wanted to restore religious fervor the American congregations. He preached in Philadelphia, Georgia and New England. Even Ben Franklin went to see Whitefield preach. He was responsible for a lot of religious rebirths. 38. John Lock e (150): John Locke was a philosopher who argued that humanity is a product of the environment. Therefore, the best way to improve society and human nature was to use and improve reason. 39. Enlightenment (149): The Enlightenment was all about reason, science and freedoms. Enlightened thinkers were willing to disregard religious beliefs in favor of more rational ideas. As a result, the colonies became less religious. 40. Great Awakening (154): The Great Awakening affected all 13 of the colonies. George Whitefield basically started it. It led people to embrace religion again as they did before the Enlightenment. 41. New Lights (158): New Lights was one of the divisions of the Congregationalists. Many went over to the Baptists or Presbyterians. This was a result of the Great Awakening undermining churches. 42. Old Lights (158): Old Lights was one of the divisions of the Congregationalists. This was a result of the Great Awakening undermining churches. 43. Navigation Acts (163): The Navigation Act of 1651 required that goods imported to England or the colonies must be on English ships whose crew was mostly English. The Navigation Act of 1660 said that the crew had to be at least ? English, not just mostly. It also said certain goods could only be shipped to England or other English colonies. The Navigation Act of 1663 said that all colonial imports from Europe to the colonies be offloaded, and have duty paid on them before their reshipment to the colonies. The Navigation Acts gave England a monopoly over tobacco and sugar. 44. Salutary neglect (168): Salutary neglect was Walpole’s relaxed policy toward the colonies that gave them greater freedoms. It ultimately led to the colonies having political independence and seeking to become independent from England. 45. George Washington (178): George Washington went to the French fort Fort Le Bouef because the French built forts in Pennsylvania to defend their interests after England got control over more land near Virginia. He went and asked the French to move and they refused. He led volunteers and their Iroquois allies to built a fort where the French had built theirs. He led an ambush on the French. The deaths during were the first tragedies of the French and Indian War. George Washington surrendered after the French attacked a month later. 46. Albany Plan of Union (179): The Albany Congress created The Albany Plan of Union in 1754. It called for a chief executive, supreme governor, and a supreme assembly. It was the basis of the current democracy system. 7. King George III (183): King George III wanted to seek peace and eventually end the French and Indian War and he forced Pitt out of office. He gave England control of most of the United States. 48. Join or Die (180): Join or Die was the first political cartoon created by Ben Franklin. It was created to unite the colonies against the French in 1754. 49. French and Indian War (177): The French and Indian War began after Virginias crossed into French territory to trade with Indians and survey land granted to them by the king. This made the French mad. In 1755, a British fleet captured Nova Scotia and killed most of its French population. The French had a victory, which demonstrated that backwoods warfare depended upon Indian allies and frontier tactics. In 1756 the colonial war became the Seven Years’ War in Europe. Pitt offered people of the colonies subsidies for their help in the war effort. The tides turned in 1758 when the English captured a French fort and the Iroquois (French allies) called off attacks on the English. 50. Treaty of Paris of 1763 (183): The Treaty of Paris of 1763 ended the French and Indian War and ended French power in America. England took all French possession east of the Mississippi River and Spanish Florida. England invited the Spanish to stay there, but most left and sold their land really cheap to the English. The lands given to the English from the French weren’t the French’s to give, it was Indian land. The Indians struck back and killed people and raided forts. These attacks convinced most colonists that Indians were bad.